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Metastatic Malignant Melanoma of the Gastrointestinal Tract: A Review

Division of Nephrology and Hypertension,  Mayo Clinic College of Medicine, Rochester,  MN 55905, USA

Keywords

Malignant Melanoma; Gastrointestinal Tract: Metastasis

Abstract

Malignant melanoma ranks among the most prevalent malignancies linked to  gastrointestinal (GI) involvement, typically presenting clinically in advanced  stages. Surgical intervention is often recommended as a palliative measure for GI  metastases. 

This case involves a 67-year-old male diagnosed with malignant melanoma  seven months prior, who presented with burning epigastric pain and bloating.  Esophagogastroduodenoscopy revealed multiple flat lesions, with biopsy results  consistent with malignant melanoma. 

Given malignant melanoma's propensity for early metastasis and its associated  high mortality rate, comprehensive evaluation and management are crucial.  As gastrointestinal involvement becomes increasingly recognized in metastatic  workups, esophagogastroduodenoscopy emerges as a vital diagnostic tool,  influencing treatment decisions and patient outcomes. While gastric metastases  remain rare, the inclusion of upper endoscopy is imperative, particularly in  symptomatic individuals, to effectively rule out metastatic disease.

Malignant melanoma ranks among the most prevalent malignancies linked to  gastrointestinal (GI) involvement, typically presenting clinically in advanced  stages. Surgical intervention is often recommended as a palliative measure for GI  metastases. 

This case involves a 67-year-old male diagnosed with malignant melanoma  seven months prior, who presented with burning epigastric pain and bloating.  Esophagogastroduodenoscopy revealed multiple flat lesions, with biopsy results  consistent with malignant melanoma. 

Given malignant melanoma's propensity for early metastasis and its associated  high mortality rate, comprehensive evaluation and management are crucial.  

As gastrointestinal involvement becomes increasingly recognized in metastatic  workups, esophagogastroduodenoscopy emerges as a vital diagnostic tool,  influencing treatment decisions and patient outcomes. While gastric metastases  remain rare, the inclusion of upper endoscopy is imperative, particularly in  symptomatic individuals, to effectively rule out metastatic disease.

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